Syntool: A Novel Region-Based Intolerance Score to Single Nucleotide Substitution for Synonymous Mutations Predictions Based on 123,136 Individuals

BACKGROUND: Synonymous mutation is the single nucleotide change that does not cause an amino acid change but can affect the rate and efficiency of translation. So recent increase in our knowledge has revealed a substantial contribution of synonymous mutations to human disease risk and other complex...

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Detalles Bibliográficos
Autores principales: Zhang, Tongda, Wu, Yiran, Lan, Zhangzhang, Shi, Quan, Yang, Ying, Guo, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546077/
https://www.ncbi.nlm.nih.gov/pubmed/28812016
http://dx.doi.org/10.1155/2017/5096208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546077/
https://www.ncbi.nlm.nih.gov/pubmed/28812016
http://dx.doi.org/10.1155/2017/5096208

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