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Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling

Responses of melanocytes (MC) to ultraviolet (UV) irradiation can be influenced by their neighbouring keratinocytes (KC). We investigated the role of Nrf2 in regulating paracrine effects of KC on UVB-induced MC responses through phosphorylation of MAPKs in association with oxidative stress in primar...

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Detalles Bibliográficos
Autores principales: Jeayeng, Saowanee, Wongkajornsilp, Adisak, Slominski, Andrzej T., Jirawatnotai, Siwanon, Sampattavanich, Somponnat, Panich, Uraiwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546090/
https://www.ncbi.nlm.nih.gov/pubmed/28495448
http://dx.doi.org/10.1016/j.freeradbiomed.2017.05.009