Cargando…

Nrf2 in keratinocytes modulates UVB-induced DNA damage and apoptosis in melanocytes through MAPK signaling

Responses of melanocytes (MC) to ultraviolet (UV) irradiation can be influenced by their neighbouring keratinocytes (KC). We investigated the role of Nrf2 in regulating paracrine effects of KC on UVB-induced MC responses through phosphorylation of MAPKs in association with oxidative stress in primar...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jeayeng, Saowanee, Wongkajornsilp, Adisak, Slominski, Andrzej T., Jirawatnotai, Siwanon, Sampattavanich, Somponnat, Panich, Uraiwan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546090/ https://www.ncbi.nlm.nih.gov/pubmed/28495448 http://dx.doi.org/10.1016/j.freeradbiomed.2017.05.009

Ejemplares similares

Activation of Nrf2 Reduces UVA-Mediated MMP-1 Upregulation via MAPK/AP-1 Signaling Cascades: The Photoprotective Effects of Sulforaphane and Hispidulin
por: Chaiprasongsuk, Anyamanee, et al.
Publicado: (2017)

Ultraviolet Radiation-Induced Skin Aging: The Role of DNA Damage and Oxidative Stress in Epidermal Stem Cell Damage Mediated Skin Aging
por: Panich, Uraiwan, et al.
Publicado: (2016)

Hydroxylumisterols, Photoproducts of Pre-Vitamin D3, Protect Human Keratinocytes against UVB-Induced Damage
por: Chaiprasongsuk, Anyamanee, et al.
Publicado: (2020)

DNA Repair Biosensor-Identified DNA Damage Activities of Endophyte Extracts from Garcinia cowa
por: Lerksuthirat, Tassanee, et al.
Publicado: (2020)

Protective effects of novel derivatives of vitamin D(3) and lumisterol against UVB-induced damage in human keratinocytes involve activation of Nrf2 and p53 defense mechanisms
por: Chaiprasongsuk, Anyamanee, et al.
Publicado: (2019)

A Case-Control Study of Involvement of Oxidative DNA Damage and Alteration of Antioxidant Defense System in Patients with Basal Cell Carcinoma: Modulation by Tumor Removal
por: Chaisiriwong, Lapatsanant, et al.
Publicado: (2016)

Melatonin and its metabolites protect human melanocytes against UVB-induced damage: Involvement of NRF2-mediated pathways
por: Janjetovic, Zorica, et al.
Publicado: (2017)

BAIAP2L1 enables cancer cell migration and facilitates phospho‐Cofilin asymmetry localization in the border cells
por: Pipatpanyanugoon, Nut, et al.
Publicado: (2021)

Comprehensive drug response profiling and pan-omic analysis identified therapeutic candidates and prognostic biomarkers for Asian cholangiocarcinoma
por: Jamnongsong, Supawan, et al.
Publicado: (2022)

The Protective Effect of Polyherbal Formulation, Harak Formula, on UVA-Induced Photoaging of Human Dermal Fibroblasts and Mouse Skin via Promoting Nrf2-Regulated Antioxidant Defense
por: Lohakul, Jinapath, et al.
Publicado: (2021)

Novel Analytical Platform For Robust Identification of Cell Migration Inhibitors
por: Somchai, Parinyachat, et al.
Publicado: (2020)

Editorial: Redox Biology of Skin Aging and Carcinogenesis: the Role of Natural Antioxidants as Potential Protective Agents
por: Panich, Uraiwan, et al.
Publicado: (2020)

Four-Octyl Itaconate Attenuates UVB-Induced Melanocytes and Keratinocytes Apoptosis by Nrf2 Activation-Dependent ROS Inhibition
por: Xie, Yongyi, et al.
Publicado: (2022)

Prinsepiae Nux Extract Activates NRF2 Activity and Protects UVB-Induced Damage in Keratinocyte
por: Wang, Shih-Han, et al.
Publicado: (2022)

The Acquired Vulnerability Caused by CDK4/6 Inhibition Promotes Drug Synergism Between Oxaliplatin and Palbociclib in Cholangiocarcinoma
por: Suppramote, Orawan, et al.
Publicado: (2022)

Role of Phytochemicals in Skin Photoprotection via Regulation of Nrf2
por: Chaiprasongsuk, Anyamanee, et al.
Publicado: (2022)

Combining the SMAC mimetic LCL161 with Gemcitabine plus Cisplatin therapy inhibits and prevents the emergence of multidrug resistance in cholangiocarcinoma
por: Prasopporn, Sunisa, et al.
Publicado: (2022)

Corrigendum: Combining the SMAC mimetic LCL161 with Gemcitabine plus Cisplatin therapy inhibits and prevents the emergence of multidrug resistance in cholangiocarcinoma
por: Prasopporn, Sunisa, et al.
Publicado: (2023)

Peroxiredoxin V Protects against UVB-Induced Damage of Keratinocytes
por: Kim, Sin Ri, et al.
Publicado: (2023)

Solamargine Alleviated UVB-Induced Inflammation and Melanogenesis in Human Keratinocytes and Melanocytes via the p38 MAPK Signaling Pathway, a Promising Agent for Post-inflammatory Hyperpigmentation
por: Zhao, Juemin, et al.
Publicado: (2022)

UVB radiation represses CYLD expression in melanocytes
por: Kuphal, Silke, et al.
Publicado: (2017)

Keratinocyte Growth Factor 2 Ameliorates UVB-Induced Skin Damage via Activating the AhR/Nrf2 Signaling Pathway
por: Gao, Shuang, et al.
Publicado: (2021)

UVB-Stimulated TNFα Release from Human Melanocyte and Melanoma Cells Is Mediated by p38 MAPK
por: Muthusamy, Visalini, et al.
Publicado: (2013)

Heat-mediated reduction of apoptosis in UVB-damaged keratinocytes in vitro and in human skin ex vivo
por: Calapre, Leslie, et al.
Publicado: (2016)

SIRT1 activation mediates heat-induced survival of UVB damaged Keratinocytes
por: Calapre, Leslie, et al.
Publicado: (2017)

Immunomodulatory Roles of Cell Cycle Regulators
por: Laphanuwat, Phatthamon, et al.
Publicado: (2019)

Photoprotection by dietary phenolics against melanogenesis induced by UVA through Nrf2-dependent antioxidant responses
por: Chaiprasongsuk, Anyamanee, et al.
Publicado: (2015)

Thymus vulgaris alleviates UVB irradiation induced skin damage via inhibition of MAPK/AP‐1 and activation of Nrf2‐ARE antioxidant system
por: Sun, Zhengwang, et al.
Publicado: (2016)

Melanocyte-keratinocyte cross-talk in vitiligo
por: Touni, Ahmed Ahmed, et al.
Publicado: (2023)

Hyperoside and Quercitrin in Houttuynia cordata Extract Attenuate UVB-Induced Human Keratinocyte Cell Damage and Oxidative Stress via Modulation of MAPKs and Akt Signaling Pathway
por: Charachit, Nattakan, et al.
Publicado: (2022)

Ultraviolet B, melanin and mitochondrial DNA: Photo-damage in human epidermal keratinocytes and melanocytes modulated by alpha-melanocyte-stimulating hormone
por: Böhm, Markus, et al.
Publicado: (2016)

Nrf2 null enhances UVB-induced skin inflammation and extracellular matrix damages
por: Saw, Constance Lay Lay, et al.
Publicado: (2014)

Redox Mechanisms of AVS022, an Oriental Polyherbal Formula, and Its Component Herbs in Protection against Induction of Matrix Metalloproteinase-1 in UVA-Irradiated Keratinocyte HaCaT Cells
por: Pluemsamran, Thanyawan, et al.
Publicado: (2013)

Ultraviolet B (UVB) activates hypothalamic-pituitary-adrenal (HPA) axis in C57BL/6 mice
por: Skobowiat, Cezary, et al.
Publicado: (2014)

Protective effect of fermented Cyclopia intermedia against UVB-induced damage in HaCaT human keratinocytes
por: Im, A-Rang, et al.
Publicado: (2016)

Melanocyte-keratinocyte interactions in vivo: the fate of melanosomes.
por: Wolff, K.
Publicado: (1973)

Nevus Depigmentosus Treated by Melanocyte–Keratinocyte Transplantation
por: Mulekar, Sanjeev V, et al.
Publicado: (2011)

Exosomes released by keratinocytes modulate melanocyte pigmentation
por: Cicero, Alessandra Lo, et al.
Publicado: (2015)

Pannexin 2 is expressed in murine skin and promotes UVB-induced apoptosis of keratinocytes
por: Sanchez-Pupo, Rafael E., et al.
Publicado: (2022)

Protective effect of different antioxidant agents in UVB-irradiated keratinocytes
por: Salucci, Sara, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_vqnhc66scht4i3cgpne5rmhlfc