Mitochondrial ASncmtRNA-1 and ASncmtRNA-2 as potent targets to inhibit tumor growth and metastasis in the RenCa murine renal adenocarcinoma model

Knockdown of antisense noncoding mitochondrial RNAs (ASncmtRNAs) induces apoptosis in several human and mouse tumor cell lines, but not normal cells, suggesting this approach for a selective therapy against different types of cancer. Here we show that in vitro knockdown of murine ASncmtRNAs induces...

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Detalles Bibliográficos
Autores principales: Borgna, Vincenzo, Villegas, Jaime, Burzio, Verónica A., Belmar, Sebastián, Araya, Mariela, Jeldes, Emanuel, Lobos-González, Lorena, Silva, Verónica, Villota, Claudio, Oliveira-Cruz, Luciana, Lopez, Constanza, Socias, Teresa, Castillo, Octavio, Burzio, Luis O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546434/
https://www.ncbi.nlm.nih.gov/pubmed/28620146
http://dx.doi.org/10.18632/oncotarget.18460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546434/
https://www.ncbi.nlm.nih.gov/pubmed/28620146
http://dx.doi.org/10.18632/oncotarget.18460

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