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Whole-exome sequencing identified genetic risk factors for asparaginase-related complications in childhood ALL patients
Allergy, pancreatitis and thrombosis are common side-effects of childhood acute lymphoblastic leukemia (ALL) treatment that are associated with the use of asparaginase (ASNase), a key component in most ALL treatment protocols. Starting with predicted functional germline variants obtained through who...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546438/ https://www.ncbi.nlm.nih.gov/pubmed/28574850 http://dx.doi.org/10.18632/oncotarget.17959 |