Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma

A putative tumor suppressor BLU mapped on the chromosomal 3p21 region, is frequently lost in human tumors including nasopharyngeal carcinoma (NPC). To explore the underlying mechanism of tumor suppression by BLU, its potential to promote apoptosis induced by TRAIL, an effector molecule elaborated by...

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Detalles Bibliográficos
Autores principales: Zhou, Jiahui, Huang, Zunnan, Wang, Ziyou, Liu, Shumin, Grandien, Alf, Ernberg, Ingemar, He, Zhiwei, Zhang, Xiangning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546445/
https://www.ncbi.nlm.nih.gov/pubmed/28029652
http://dx.doi.org/10.18632/oncotarget.14126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546445/
https://www.ncbi.nlm.nih.gov/pubmed/28029652
http://dx.doi.org/10.18632/oncotarget.14126

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