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Tumor suppressor BLU promotes TRAIL-induced apoptosis by downregulating NF-κB signaling in nasopharyngeal carcinoma
A putative tumor suppressor BLU mapped on the chromosomal 3p21 region, is frequently lost in human tumors including nasopharyngeal carcinoma (NPC). To explore the underlying mechanism of tumor suppression by BLU, its potential to promote apoptosis induced by TRAIL, an effector molecule elaborated by...
Autores principales: | Zhou, Jiahui, Huang, Zunnan, Wang, Ziyou, Liu, Shumin, Grandien, Alf, Ernberg, Ingemar, He, Zhiwei, Zhang, Xiangning |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546445/ https://www.ncbi.nlm.nih.gov/pubmed/28029652 http://dx.doi.org/10.18632/oncotarget.14126 |
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