Epigenetic modifiers upregulate MHC II and impede ovarian cancer tumor growth

Expression of MHC class II pathway proteins in ovarian cancer correlates with prolonged survival. Murine and human ovarian cancer cells were treated with epigenetic modulators – histone deacetylase inhibitors and a DNA methyltransferase inhibitor. mRNA and protein expression of the MHC II pathway we...

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Detalles Bibliográficos
Autores principales: Turner, Taylor B, Meza-Perez, Selene, Londoño, Angelina, Katre, Ashwini, Peabody, Jacelyn E., Smith, Haller J., Forero, Andres, Norian, Lyse A, Straughn, J. Michael, Buchsbaum, Donald J., Rand all, Troy D., Arend, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546470/
https://www.ncbi.nlm.nih.gov/pubmed/28498806
http://dx.doi.org/10.18632/oncotarget.17395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546470/
https://www.ncbi.nlm.nih.gov/pubmed/28498806
http://dx.doi.org/10.18632/oncotarget.17395

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