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Impact of chronic unpredicted mild stress-induced depression on repaglinide fate via glucocorticoid signaling pathway

Chronic unpredicted mild stress (CUMS)-induced depression could alter the pharmacokinetics of many drugs in rats, however, the underlying mechanism is not clear. In this work we studied the pharmacokinetics of repaglinide, and explored the role of glucocorticoid and adrenergic signaling pathway in r...

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Detalles Bibliográficos
Autores principales: Wei, Hongyan, Zhou, Ting, Tan, Boyu, Zhang, Lei, Li, Mingming, Xiao, Zhijun, Xu, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546485/
https://www.ncbi.nlm.nih.gov/pubmed/28574832
http://dx.doi.org/10.18632/oncotarget.17874