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Cell type-dependent HIF1 α-mediated effects of hypoxia on proliferation, migration and metastatic potential of human tumor cells

Tumor hypoxia promotes neoangiogenesis and contributes to the radio- and chemotherapy resistant and aggressive phenotype of cancer cells. However, the migratory response of tumor cells and the role of small GTPases regulating the organization of cytoskeleton under hypoxic conditions have yet to be e...

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Detalles Bibliográficos
Autores principales: Tátrai, Enikő, Bartal, Alexandra, Gacs, Alexandra, Paku, Sándor, Kenessey, István, Garay, Tamás, Hegedűs, Balázs, Molnár, Eszter, Cserepes, Mihály T., Hegedűs, Zita, Kucsma, Nóra, Szakács, Gergely, Tóvári, József
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546497/
https://www.ncbi.nlm.nih.gov/pubmed/28562340
http://dx.doi.org/10.18632/oncotarget.17806