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The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers

A key task in developing the field of personalized cancer therapy is the identification of novel molecular targets that enable treatment of cancers not susceptible to other means of specific therapy. The collagen receptor uPARAP/Endo180 is overexpressed by malignant cells in several non-epithelial c...

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Detalles Bibliográficos
Autores principales: Nielsen, Christoffer Fagernæs, van Putten, Sander Maarten, Lund, Ida Katrine, Melander, Maria Carlsén, Nørregaard, Kirstine Sandal, Jürgensen, Henrik Jessen, Reckzeh, Kristian, Christensen, Kristine Rothaus, Ingvarsen, Signe Ziir, Gårdsvoll, Henrik, Jensen, Kamilla Ellermann, Hamerlik, Petra, Engelholm, Lars Henning, Behrendt, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546505/
https://www.ncbi.nlm.nih.gov/pubmed/28574834
http://dx.doi.org/10.18632/oncotarget.17883