FOXP3 inhibits cancer stem cell self-renewal via transcriptional repression of COX2 in colorectal cancer cells

Colon cancer stem cell (cCSC) is considered as the seed cell of colon cancer initiation and metastasis. Cyclooxygenase-2 (COX2), a downstream target of NFκB, is found to be essential in promoting cancer stem cell renewal. However, how COX2 is dysregulated in cCSCs is largely unknown. In this study,...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Shuo, Zhang, Cun, Zhang, Kuo, Gao, Yuan, Wang, Zhaowei, Li, Xiaoju, Cheng, Guang, Wang, Shuning, Xue, Xiaochang, Li, Weina, Zhang, Wei, Zhang, Yingqi, Xing, Xianghui, Li, Meng, Hao, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546511/
https://www.ncbi.nlm.nih.gov/pubmed/28591725
http://dx.doi.org/10.18632/oncotarget.17974

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546511/
https://www.ncbi.nlm.nih.gov/pubmed/28591725
http://dx.doi.org/10.18632/oncotarget.17974

Ejemplares similares