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Dynamic changes in clonal cytogenetic architecture during progression of chronic lymphocytic leukemia in patients and patient-derived murine xenografts

Subclonal heterogeneity and clonal selection influences disease progression in chronic lymphocytic leukemia (CLL). It is therefore important that therapeutic decisions are made based on an understanding of the CLL clonal architecture and its dynamics in individual patients. Identification of cytogen...

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Detalles Bibliográficos
Autores principales: Davies, Nicholas J., Kwok, Marwan, Gould, Clive, Oldreive, Ceri E., Mao, Jingwen, Parry, Helen, Smith, Edward, Agathanggelou, Angelo, Pratt, Guy, Taylor, Alexander Malcolm R., Moss, Paul, Griffiths, Mike, Stankovic, Tatjana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546515/
https://www.ncbi.nlm.nih.gov/pubmed/28496009
http://dx.doi.org/10.18632/oncotarget.17432