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The dark side of SOX2: cancer - a comprehensive overview

The pluripotency-associated transcription factor SOX2 is essential during mammalian embryogenesis and later in life, but SOX2 expression can also be highly detrimental. Over the past 10 years, SOX2 has been shown to be expressed in at least 25 different cancers. This review provides a comprehensive...

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Detalles Bibliográficos
Autores principales: Wuebben, Erin L., Rizzino, Angie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546531/
https://www.ncbi.nlm.nih.gov/pubmed/28388544
http://dx.doi.org/10.18632/oncotarget.16570