Establishment of highly metastatic KRAS mutant lung cancer cell sublines in long-term three-dimensional low attachment cultures

Decreased cell-substratum adhesion is crucially involved in metastasis. Previous studies demonstrated that lung cancer with floating cell clusters in histology is more likely to develop metastasis. In the present study, we investigated whether cancer cells in long-term, three-dimensional low attachm...

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Detalles Bibliográficos
Autores principales: Nakano, Tomoyuki, Kanai, Yoshihiko, Amano, Yusuke, Yoshimoto, Taichiro, Matsubara, Daisuke, Shibano, Tomoki, Tamura, Tomoko, Oguni, Sachiko, Katashiba, Shizuka, Ito, Takeshi, Murakami, Yoshinori, Fukayama, Masashi, Murakami, Takashi, Endo, Shunsuke, Niki, Toshiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546599/
https://www.ncbi.nlm.nih.gov/pubmed/28786996
http://dx.doi.org/10.1371/journal.pone.0181342

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546599/
https://www.ncbi.nlm.nih.gov/pubmed/28786996
http://dx.doi.org/10.1371/journal.pone.0181342

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