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The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection

Entero virus 71 (EV71) causes hand, foot, and mouth disease (HFMD) and occasionally leads to severe neurological complications and even death. Scavenger receptor class B member 2 (SCARB2) is a functional receptor for EV71, that mediates viral attachment, internalization, and uncoating. However, the...

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Detalles Bibliográficos
Autores principales: Zhang, Xuyuan, Yang, Pan, Wang, Nan, Zhang, Jialong, Li, Jingyun, Guo, Hao, Yin, Xiangyun, Rao, Zihe, Wang, Xiangxi, Zhang, Liguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Higher Education Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546930/
https://www.ncbi.nlm.nih.gov/pubmed/28447294
http://dx.doi.org/10.1007/s13238-017-0405-7