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The binding of a monoclonal antibody to the apical region of SCARB2 blocks EV71 infection
Entero virus 71 (EV71) causes hand, foot, and mouth disease (HFMD) and occasionally leads to severe neurological complications and even death. Scavenger receptor class B member 2 (SCARB2) is a functional receptor for EV71, that mediates viral attachment, internalization, and uncoating. However, the...
Autores principales: | Zhang, Xuyuan, Yang, Pan, Wang, Nan, Zhang, Jialong, Li, Jingyun, Guo, Hao, Yin, Xiangyun, Rao, Zihe, Wang, Xiangxi, Zhang, Liguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546930/ https://www.ncbi.nlm.nih.gov/pubmed/28447294 http://dx.doi.org/10.1007/s13238-017-0405-7 |
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