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Increasing the safety and efficacy of chimeric antigen receptor T cell therapy
Chimeric antigen receptor (CAR) T cell therapy is a promising cancer treatment that has recently been undergoing rapid development. However, there are still some major challenges, including precise tumor targeting to avoid off-target or “on-target/off-tumor” toxicity, adequate T cell infiltration an...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Higher Education Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5546931/ https://www.ncbi.nlm.nih.gov/pubmed/28434147 http://dx.doi.org/10.1007/s13238-017-0411-9 |