A camelid single-domain antibody neutralizes botulinum neurotoxin A by blocking host receptor binding

Antibody treatment is currently the only available countermeasure for botulism, a fatal illness caused by flaccid paralysis of muscles due to botulinum neurotoxin (BoNT) intoxication. Among the seven major serotypes of BoNT/A-G, BoNT/A poses the most serious threat to humans because of its high pote...

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Detalles Bibliográficos
Autores principales: Yao, Guorui, Lam, Kwok-ho, Weisemann, Jasmin, Peng, Lisheng, Krez, Nadja, Perry, Kay, Shoemaker, Charles B., Dong, Min, Rummel, Andreas, Jin, Rongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547058/
https://www.ncbi.nlm.nih.gov/pubmed/28785006
http://dx.doi.org/10.1038/s41598-017-07457-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547058/
https://www.ncbi.nlm.nih.gov/pubmed/28785006
http://dx.doi.org/10.1038/s41598-017-07457-5

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