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Genuine antiplasticizing effect of water on a glass-former drug

Water is the most important plasticizer of biological and organic hydrophilic materials, which generally exhibit enhanced mechanical softness and molecular mobility upon hydration. The enhancement of the molecular dynamics upon mixing with water, which in glass-forming systems implies a lower glass...

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Detalles Bibliográficos
Autores principales: Ruiz, Guadalupe N., Romanini, Michela, Hauptmann, Astrid, Loerting, Thomas, Shalaev, Evgenyi, Tamarit, Josep Ll., Pardo, Luis C., Macovez, Roberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547059/
https://www.ncbi.nlm.nih.gov/pubmed/28785030
http://dx.doi.org/10.1038/s41598-017-07643-5