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Genuine antiplasticizing effect of water on a glass-former drug
Water is the most important plasticizer of biological and organic hydrophilic materials, which generally exhibit enhanced mechanical softness and molecular mobility upon hydration. The enhancement of the molecular dynamics upon mixing with water, which in glass-forming systems implies a lower glass...
Autores principales: | Ruiz, Guadalupe N., Romanini, Michela, Hauptmann, Astrid, Loerting, Thomas, Shalaev, Evgenyi, Tamarit, Josep Ll., Pardo, Luis C., Macovez, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547059/ https://www.ncbi.nlm.nih.gov/pubmed/28785030 http://dx.doi.org/10.1038/s41598-017-07643-5 |
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