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Inhibition of glycogen synthase kinase-3 by BTA-EG(4) reduces tau abnormalities in an organotypic brain slice culture model of Alzheimer’s disease

Organotypic brain slice culture models provide an alternative to early stage in vivo studies as an integrated tissue system that can recapitulate key disease features, thereby providing an excellent platform for drug screening. We recently described a novel organotypic 3xTg-AD mouse brain slice cult...

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Detalles Bibliográficos
Autores principales: Croft, Cara L., Kurbatskaya, Ksenia, Hanger, Diane P., Noble, Wendy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547074/
https://www.ncbi.nlm.nih.gov/pubmed/28785087
http://dx.doi.org/10.1038/s41598-017-07906-1