Ensa controls S-phase length by modulating Treslin levels

The Greatwall/Ensa/PP2A-B55 pathway is essential for controlling mitotic substrate phosphorylation and mitotic entry. Here, we investigate the effect of the knockdown of the Gwl substrate, Ensa, in human cells. Unexpectedly, Ensa knockdown promotes a dramatic extension of S phase associated with a l...

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Detalles Bibliográficos
Autores principales: Charrasse, Sophie, Gharbi-Ayachi, Aicha, Burgess, Andrew, Vera, Jorge, Hached, Khaled, Raynaud, Peggy, Schwob, Etienne, Lorca, Thierry, Castro, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547116/
https://www.ncbi.nlm.nih.gov/pubmed/28785014
http://dx.doi.org/10.1038/s41467-017-00339-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547116/
https://www.ncbi.nlm.nih.gov/pubmed/28785014
http://dx.doi.org/10.1038/s41467-017-00339-4

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