Cargando…

Ensa controls S-phase length by modulating Treslin levels

The Greatwall/Ensa/PP2A-B55 pathway is essential for controlling mitotic substrate phosphorylation and mitotic entry. Here, we investigate the effect of the knockdown of the Gwl substrate, Ensa, in human cells. Unexpectedly, Ensa knockdown promotes a dramatic extension of S phase associated with a l...

Descripción completa

Detalles Bibliográficos
Autores principales:	Charrasse, Sophie, Gharbi-Ayachi, Aicha, Burgess, Andrew, Vera, Jorge, Hached, Khaled, Raynaud, Peggy, Schwob, Etienne, Lorca, Thierry, Castro, Anna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547116/ https://www.ncbi.nlm.nih.gov/pubmed/28785014 http://dx.doi.org/10.1038/s41467-017-00339-4

Ejemplares similares

ENSA and ARPP19 differentially control cell cycle progression and development
por: Hached, Khaled, et al.
Publicado: (2019)

Cyclin-dependent kinase regulates the length of S phase through TICRR/TRESLIN phosphorylation
por: Sansam, Courtney G., et al.
Publicado: (2015)

Cdks put Treslin on TopBP1
por: Short, Ben
Publicado: (2011)

Direct regulation of Treslin by cyclin-dependent kinase is essential for the onset of DNA replication
por: Kumagai, Akiko, et al.
Publicado: (2011)

Refining the domain architecture model of the replication origin firing factor Treslin/TICRR
por: Ferreira, Pedro, et al.
Publicado: (2022)

The TRESLIN-MTBP complex couples completion of DNA replication with S/G2 transition
por: Zonderland, Gijs, et al.
Publicado: (2022)

The role of DDK and Treslin–MTBP in coordinating replication licensing and pre-initiation complex formation
por: Volpi, Ilaria, et al.
Publicado: (2021)

Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1
por: Lagirand-Cantaloube, Julie, et al.
Publicado: (2017)

Copy number amplification of ENSA promotes the progression of triple-negative breast cancer via cholesterol biosynthesis
por: Chen, Yi-Yu, et al.
Publicado: (2022)

Binding of the Treslin-MTBP Complex to Specific Regions of the Human Genome Promotes the Initiation of DNA Replication
por: Kumagai, Akiko, et al.
Publicado: (2020)

The CRL4(DTL) E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase
por: Wittig, Kimberlie A, et al.
Publicado: (2021)

PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
por: Hégarat, Nadia, et al.
Publicado: (2014)

The BEG (PP2A-B55/ENSA/Greatwall) Pathway Ensures Cytokinesis follows Chromosome Separation
por: Cundell, Michael J., et al.
Publicado: (2013)

Correction: PP2A/B55 and Fcp1 Regulate Greatwall and Ensa Dephosphorylation during Mitotic Exit
Publicado: (2014)

The MASTL-ENSA-PP2A/B55 axis modulates cisplatin resistance in oral squamous cell carcinoma
por: Gouttia, Odjo G., et al.
Publicado: (2022)

MTBP, the partner of Treslin, contains a novel DNA-binding domain that is essential for proper initiation of DNA replication
por: Kumagai, Akiko, et al.
Publicado: (2017)

Intra-S phase checkpoint kinase Chk1 dissociates replication proteins Treslin and TopBP1 through multiple mechanisms during replication stress
por: Kelly, Rebecca L., et al.
Publicado: (2022)

PP2A-B55 Holoenzyme Regulation and Cancer
por: Goguet-Rubio, Perrine, et al.
Publicado: (2020)

Quantitative Live Imaging of Endogenous DNA Replication in Mammalian Cells
por: Burgess, Andrew, et al.
Publicado: (2012)

Partial inhibition of Cdk1 in G(2) phase overrides the SAC and decouples mitotic events
por: McCloy, Rachael A, et al.
Publicado: (2014)

The Cell Cycle Checkpoint System MAST(L)-ENSA/ARPP19-PP2A is Targeted by cAMP/PKA and cGMP/PKG in Anucleate Human Platelets
por: Kumm, Elena J., et al.
Publicado: (2020)

DNA replication and spindle checkpoints cooperate during S phase to delay mitosis and preserve genome integrity
por: Magiera, Maria M., et al.
Publicado: (2014)

Measuring S-Phase Duration from Asynchronous Cells Using Dual EdU-BrdU Pulse-Chase Labeling Flow Cytometry
por: Bialic, Marta, et al.
Publicado: (2022)

Metabolic and Environmental Conditions Determine Nuclear Genomic Instability in Budding Yeast Lacking Mitochondrial DNA
por: Dirick, Léon, et al.
Publicado: (2013)

N-cadherin–dependent cell–cell contact regulates Rho GTPases and β-catenin localization in mouse C2C12 myoblasts
por: Charrasse, Sophie, et al.
Publicado: (2002)

Changing Mad2 Levels Affects Chromosome Segregation and Spindle Assembly Checkpoint Control in Female Mouse Meiosis I
por: Niault, Théodora, et al.
Publicado: (2007)

Rab35 regulates cadherin-mediated adherens junction formation and myoblast fusion
por: Charrasse, Sophie, et al.
Publicado: (2013)

Homeostatic control of START through negative feedback between Cln3-Cdk1 and Rim15/Greatwall kinase in budding yeast
por: Talarek, Nicolas, et al.
Publicado: (2017)

Structural, enzymatic and spatiotemporal regulation of PP2A-B55 phosphatase in the control of mitosis
por: Lacroix, Benjamin, et al.
Publicado: (2022)

A Group of Olfactory Receptor Alleles that Encode Full Length Proteins are Down-Regulated as Olfactory Sensory Neurons Mature
por: Krolewski, Richard C., et al.
Publicado: (2020)

ADP-Ribosylation Factor 6 Regulates Mammalian Myoblast Fusion through Phospholipase D1 and Phosphatidylinositol 4,5-Bisphosphate Signaling Pathways
por: Bach, Anne-Sophie, et al.
Publicado: (2010)

Greatwall promotes cell transformation by hyperactivating AKT in human malignancies
por: Vera, Jorge, et al.
Publicado: (2015)

Surface functionalization by covalent immobilization of an innovative carvacrol derivative to avoid fungal biofilm formation
por: Gharbi, Aïcha, et al.
Publicado: (2015)

Trypanosomiasis of camels (Camelus dromedarius) in Algeria: First report
por: Bennoune, Omar, et al.
Publicado: (2013)

Bread Surplus: A Cumulative Waste or a Staple Material for High-Value Products?
por: Ben Rejeb, Ines, et al.
Publicado: (2022)

Do Bradykinesia and Tremor Interfere in Voluntary Movement of Essential Tremor Patients? Preliminary Findings
por: Goubault, Etienne, et al.
Publicado: (2017)

Long Carbon Fibers for Microwave Absorption: Effect of Fiber Length on Absorption Frequency Band
por: Breiss, Hanadi, et al.
Publicado: (2020)

Erratum to: Surface functionalization by covalent immobilization of an innovative carvacrol derivative to avoid fungal biofilm formation
por: Gharbi, Aïcha, et al.
Publicado: (2015)

Molecular length distribution and the formation of smectic phases
por: Kapernaum, Nadia, et al.
Publicado: (2009)

Transverse phase-plane clipping of bunch length
por: Schnell, Wolfgang
Publicado: (1988)

Cannot write session to /tmp/vufind_sessions/sess_f4mbbdno7c2ui5jfrd7tsecutq