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Polymer-encased nanodiscs with improved buffer compatibility

Styrene-maleic acid copolymers allow for solubilization and reconstitution of membrane proteins into nanodiscs. These polymer-encased nanodiscs are promising platforms for studies of membrane proteins in a near-physiologic environment without the use of detergents. However, current styrene-maleic ac...

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Detalles Bibliográficos
Autores principales: Fiori, Mariana C., Jiang, Yunjiang, Altenberg, Guillermo A., Liang, Hongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547149/
https://www.ncbi.nlm.nih.gov/pubmed/28785023
http://dx.doi.org/10.1038/s41598-017-07110-1