Induction of G2M Arrest by Flavokawain A, a Kava Chalcone, Increases the Responsiveness of HER2-Overexpressing Breast Cancer Cells to Herceptin

HER2/neu positive breast tumors predict a high mortality and comprise 25%–30% of breast cancer. We have shown that Flavokawain A (FKA) preferentially reduces the viabilities of HER2-overexpressing breast cancer cell lines (i.e., SKBR3 and MCF7/HER2) versus those with less HER2 expression (i.e., MCF7...

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Detalles Bibliográficos
Autores principales: Jandial, Danielle D., Krill, Lauren S., Chen, Lixia, Wu, Chunli, Ke, Yu, Xie, Jun, Hoang, Bang H., Zi, Xiaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547191/
https://www.ncbi.nlm.nih.gov/pubmed/28335434
http://dx.doi.org/10.3390/molecules22030462

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547191/
https://www.ncbi.nlm.nih.gov/pubmed/28335434
http://dx.doi.org/10.3390/molecules22030462

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