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O-GlcNAcylation of NF-κB Promotes Lung Metastasis of Cervical Cancer Cells via Upregulation of CXCR4 Expression

C-X-C chemokine receptor 4 (CXCR4) stimulates cancer metastasis. NF-κB regulates CXCR4 expression in cancer cells, and O-GlcNAc modification of NF-κB promotes its transcriptional activity. Here, we determined whether CXCR4 expression is affected by O-GlcNAcylation of NF-κB in lung metastasis of cerv...

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Detalles Bibliográficos
Autores principales: Ali, Akhtar, Kim, Sung Hwan, Kim, Min Jun, Choi, Mee Young, Kang, Sang Soo, Cho, Gyeong Jae, Kim, Yoon Sook, Choi, Jun-Young, Choi, Wan Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547217/
https://www.ncbi.nlm.nih.gov/pubmed/28681591
http://dx.doi.org/10.14348/molcells.2017.2309