Modulation of Mitochondrial Membrane Potential and ROS Generation by Nicotinamide in a Manner Independent of SIRT1 and Mitophagy

Nicotinamide (NAM) plays essential roles in physiology through facilitating NAD(+) redox homeostasis. Importantly, at high doses, it protects cells under oxidative stresses, and has shown therapeutic effectiveness in a variety of disease conditions. In our previous studies, NAM lowered reactive oxyg...

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Detalles Bibliográficos
Autores principales: Song, Seon Beom, Jang, So-Young, Kang, Hyun Tae, Wei, Bie, Jeoun, Un-woo, Yoon, Gye Soon, Hwang, Eun Seong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Molecular and Cellular Biology 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547220/
https://www.ncbi.nlm.nih.gov/pubmed/28736426
http://dx.doi.org/10.14348/molcells.2017.0081

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547220/
https://www.ncbi.nlm.nih.gov/pubmed/28736426
http://dx.doi.org/10.14348/molcells.2017.0081

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