Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters

BACKGROUND: The association of active transcription regulatory elements (TREs) with DNAse I hypersensitivity (DHS[+]) and an ‘open’ local chromatin configuration has long been known. However, the 3D topography of TREs within the nuclear landscape of individual cells in relation to their active or in...

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Detalles Bibliográficos
Autores principales: Cremer, Marion, Schmid, Volker J., Kraus, Felix, Markaki, Yolanda, Hellmann, Ines, Maiser, Andreas, Leonhardt, Heinrich, John, Sam, Stamatoyannopoulos, John, Cremer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547466/
https://www.ncbi.nlm.nih.gov/pubmed/28784182
http://dx.doi.org/10.1186/s13072-017-0146-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547466/
https://www.ncbi.nlm.nih.gov/pubmed/28784182
http://dx.doi.org/10.1186/s13072-017-0146-0

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