Large scale genomic reorganization of topological domains at the HoxD locus

BACKGROUND: The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster. In particular, the activation of the most posterior HoxD genes in developing digits is controlled by r...

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Detalles Bibliográficos
Autores principales: Fabre, Pierre J., Leleu, Marion, Mormann, Benjamin H., Lopez-Delisle, Lucille, Noordermeer, Daan, Beccari, Leonardo, Duboule, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547506/
https://www.ncbi.nlm.nih.gov/pubmed/28784160
http://dx.doi.org/10.1186/s13059-017-1278-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547506/
https://www.ncbi.nlm.nih.gov/pubmed/28784160
http://dx.doi.org/10.1186/s13059-017-1278-z

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