Cargando…

Large scale genomic reorganization of topological domains at the HoxD locus

BACKGROUND: The transcriptional activation of HoxD genes during mammalian limb development involves dynamic interactions with two topologically associating domains (TADs) flanking the HoxD cluster. In particular, the activation of the most posterior HoxD genes in developing digits is controlled by r...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fabre, Pierre J., Leleu, Marion, Mormann, Benjamin H., Lopez-Delisle, Lucille, Noordermeer, Daan, Beccari, Leonardo, Duboule, Denis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547506/ https://www.ncbi.nlm.nih.gov/pubmed/28784160 http://dx.doi.org/10.1186/s13059-017-1278-z

Ejemplares similares

Chromatin topology and the timing of enhancer function at the HoxD locus
por: Rodríguez-Carballo, Eddie, et al.
Publicado: (2020)

Similarities and differences in the regulation of HoxD genes during chick and mouse limb development
por: Yakushiji-Kaminatsui, Nayuta, et al.
Publicado: (2018)

Sequential in cis mutagenesis in vivo reveals various functions for CTCF sites at the mouse HoxD cluster
por: Amândio, Ana Rita, et al.
Publicado: (2021)

A role for HOX13 proteins in the regulatory switch between TADs at the HoxD locus
por: Beccari, Leonardo, et al.
Publicado: (2016)

The HoxD cluster is a dynamic and resilient TAD boundary controlling the segregation of antagonistic regulatory landscapes
por: Rodríguez-Carballo, Eddie, et al.
Publicado: (2017)

Conservation and Divergence of Regulatory Strategies at Hox Loci and the Origin of Tetrapod Digits
por: Woltering, Joost M., et al.
Publicado: (2014)

Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations
por: Bolt, Christopher Chase, et al.
Publicado: (2021)

A Genetic Approach to the Recruitment of PRC2 at the HoxD Locus
por: Schorderet, Patrick, et al.
Publicado: (2013)

Temporal dynamics and developmental memory of 3D chromatin architecture at Hox gene loci
por: Noordermeer, Daan, et al.
Publicado: (2014)

Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr
por: Zakany, Jozsef, et al.
Publicado: (2017)

Dissecting CTCF site function in a tense HoxD locus
por: Bruneau, Benoit G.
Publicado: (2021)

Making HoxD waves
por: Katsnelson, Alla
Publicado: (2006)

The constrained architecture of mammalian Hox gene clusters
por: Darbellay, Fabrice, et al.
Publicado: (2019)

Impact of genome architecture on the functional activation and repression of Hox regulatory landscapes
por: Rodríguez-Carballo, Eddie, et al.
Publicado: (2019)

Heterogeneous combinatorial expression of Hoxd genes in single cells during limb development
por: Fabre, P. J., et al.
Publicado: (2018)

Sequential and directional insulation by conserved CTCF sites underlies the Hox timer in stembryos
por: Rekaik, Hocine, et al.
Publicado: (2023)

Bat Accelerated Regions Identify a Bat Forelimb Specific Enhancer in the HoxD Locus
por: Booker, Betty M., et al.
Publicado: (2016)

Developmental and evolutionary comparative analysis of a regulatory landscape in mouse and chicken
por: Hintermann, Aurélie, et al.
Publicado: (2022)

Distinct Roles and Regulations for Hoxd Genes in Metanephric Kidney Development
por: Di-Poï, Nicolas, et al.
Publicado: (2007)

HOX13 proteins: the molecular switcher in Hoxd bimodal regulation
por: Ros, Marian A.
Publicado: (2016)

Extreme conservation of noncoding DNA near HoxD complex of vertebrates
por: Sabarinadh, Chilaka, et al.
Publicado: (2004)

Physical Forces May Cause the HoxD Gene Cluster Elongation
por: Papageorgiou, Spyros
Publicado: (2017)

HoxA and HoxD expression in a variety of vertebrate body plan features reveals an ancient origin for the distal Hox program
por: Archambeault, Sophie, et al.
Publicado: (2014)

Dbx2 regulation in limbs suggests interTAD sharing of enhancers
por: Beccari, Leonardo, et al.
Publicado: (2021)

Chromatin organization and global regulation of Hox gene clusters
por: Montavon, Thomas, et al.
Publicado: (2013)

Ultraconserved Sequences Associated with HoxD Cluster Have Strong Repression Activity
por: Kushawah, Gopal, et al.
Publicado: (2017)

Embryonic timing, axial stem cells, chromatin dynamics, and the Hox clock
por: Deschamps, Jacqueline, et al.
Publicado: (2017)

Key pathways regulated by HoxA9,10,11/HoxD9,10,11 during limb development
por: Raines, Anna M., et al.
Publicado: (2015)

Conserved elements within open reading frames of mammalian Hox genes
por: Woltering, Joost M, et al.
Publicado: (2009)

The Evolution of HoxD-11 Expression in the Bird Wing: Insights from Alligator mississippiensis
por: Vargas, Alexander O., et al.
Publicado: (2008)

Uncoupling Time and Space in the Collinear Regulation of Hox Genes
por: Tschopp, Patrick, et al.
Publicado: (2009)

HoxD expression in the fin-fold compartment of basal gnathostomes and implications for paired appendage evolution
por: Tulenko, Frank J., et al.
Publicado: (2016)

Trimethylation of Histone 3 lysine 27 (H3K27me3) ChIP-PCR and transcriptional expression data of Ef1-alpha, cyp26A, HoxC10, HoxD10 and HoxD11 in the Xenopus XTC cell line
por: Vieira, Warren, et al.
Publicado: (2017)

Reorganisation of Hoxd regulatory landscapes during the evolution of a snake-like body plan
por: Guerreiro, Isabel, et al.
Publicado: (2016)

Comparative analyses of vertebrate posterior HoxD clusters reveal atypical cluster architecture in the caecilian Typhlonectes natans
por: Mannaert, An, et al.
Publicado: (2010)

A functionally conserved Polycomb response element from mouse HoxD complex responds to heterochromatin factors
por: Vasanthi, Dasari, et al.
Publicado: (2013)

The posterior HOXD locus: Its contribution to phenotype and malignancy of Ewing sarcoma
por: von Heyking, Kristina, et al.
Publicado: (2016)

A complex regulatory landscape involved in the development of mammalian external genitals
por: Amândio, Ana Rita, et al.
Publicado: (2020)

Progressive Genomic Instability in the Nup98-HoxD13 Model of MDS Correlates with Loss of the PIG-A Gene Product()()
por: Byrne, Michael, et al.
Publicado: (2014)

Attenuated Acceleration to Leukemia after Ezh2 Loss in Nup98-HoxD13 (NHD13) Myelodysplastic Syndrome
por: Ling, Victoria Y., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ukaltukrd2146otubn5qgh90rj