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Secretory RAB GTPase 3C modulates IL6-STAT3 pathway to promote colon cancer metastasis and is associated with poor prognosis

BACKGROUND: RAB GTPases are important in the regulation of membrane trafficking and cell movement. Recently, exocytic RABs have received increasing attention in cancer research. However, the functional roles of exocytic RABs in colorectal carcinogenesis remain to be elucidated. METHODS: Immunohistoc...

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Detalles Bibliográficos
Autores principales: Chang, Yu-Chan, Su, Chia-Yi, Chen, Ming-Huang, Chen, Wei-Shone, Chen, Chi-Long, Hsiao, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547507/
https://www.ncbi.nlm.nih.gov/pubmed/28784136
http://dx.doi.org/10.1186/s12943-017-0687-7