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Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena

Hypoxia is a classic feature of the tumor microenvironment with a profound impact on cancer progression and therapeutic response. Activation of complex hypoxia pathways orchestrated by the transcription factor HIF (hypoxia-inducible factor) contributes to aggressive phenotypes and metastasis in nume...

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Detalles Bibliográficos
Autores principales: Shih, Jing-Wen, Kung, Hsing-Jien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547530/
https://www.ncbi.nlm.nih.gov/pubmed/28789687
http://dx.doi.org/10.1186/s12929-017-0358-4