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Long non-coding RNA and tumor hypoxia: new players ushered toward an old arena
Hypoxia is a classic feature of the tumor microenvironment with a profound impact on cancer progression and therapeutic response. Activation of complex hypoxia pathways orchestrated by the transcription factor HIF (hypoxia-inducible factor) contributes to aggressive phenotypes and metastasis in nume...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547530/ https://www.ncbi.nlm.nih.gov/pubmed/28789687 http://dx.doi.org/10.1186/s12929-017-0358-4 |