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Increased p53 immunopositivity in anaplastic medulloblastoma and supratentorial PNET is not caused by JC virus

BACKGROUND: p53 mutations are relatively uncommon in medulloblastoma, but abnormalities in this cell cycle pathway have been associated with anaplasia and worse clinical outcomes. We correlated p53 protein expression with pathological subtype and clinical outcome in 75 embryonal brain tumors. The pr...

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Detalles Bibliográficos
Autores principales: Eberhart, Charles G, Chaudhry, Aneeka, Daniel, Richard W, Khaki, Leila, Shah, Keerti V, Gravitt, Patti E
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554768/
https://www.ncbi.nlm.nih.gov/pubmed/15717928
http://dx.doi.org/10.1186/1471-2407-5-19