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Osteopontin Impacts West Nile virus Pathogenesis and Resistance by Regulating Inflammasome Components and Cell Death in the Central Nervous System at Early Time Points

Osteopontin (OPN) is a molecule that is common in central nervous system (CNS) pathologies, which participates in the activation, migration, and survival of inflammatory cells. However, the mechanisms by which OPN modulates inflammatory pathways are not clear. To understand the role of OPN in CNS vi...

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Detalles Bibliográficos
Autores principales: Bortell, Nikki, Flynn, Claudia, Conti, Bruno, Fox, Howard S., Marcondes, Maria Cecilia G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547729/
https://www.ncbi.nlm.nih.gov/pubmed/28811681
http://dx.doi.org/10.1155/2017/7582437