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Genetic linkage analysis supports the presence of two susceptibility loci for alcoholism and heavy drinking on chromosome 1p22.1-11.2 and 1q21.3-24.2

BACKGROUND: In order to confirm a previous finding of linkage to alcoholism on chromosome 1 we have carried out a genetic linkage study. METHODS: DNA from eighteen families, densely affected by alcoholism, was used to genotype a set of polymorphic microsatellite markers at loci approximately 10 cent...

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Detalles Bibliográficos
Autores principales: Guerrini, Irene, Cook, Christopher CH, Kest, Wendy, Devitgh, Audrey, McQuillin, Andrew, Curtis, David, Gurling, Hugh MD
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC554783/
https://www.ncbi.nlm.nih.gov/pubmed/15740611
http://dx.doi.org/10.1186/1471-2156-6-11