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Wild-type blocking pcr coupled with internal competitive amplified fragment improved the detection of rare mutation of KRAS

Mutant KRAS proto-oncogene GTPase (KRAS) serves an important role in predicting the development, diagnosis, treatment and efficacy of targeted drug therapies for colorectal cancer. To improve the detection efficacy of trace amount of mutant KRAS, the locked nucleic acid-based method was modified in...

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Detalles Bibliográficos
Autores principales:	Peng, Jia, Wei, Kun, Zhao, Xiang, Yang, Ke, Wang, Huan, Zhang, Yang, Guo, Mei, He, Jing, Wu, Haiyan, Li, Yongchuan, Zhao, Na, Huang, Qing, Fu, Weiling
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547944/ https://www.ncbi.nlm.nih.gov/pubmed/28677778 http://dx.doi.org/10.3892/mmr.2017.6883

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