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Hypertrophic differentiation of mesenchymal stem cells is suppressed by xanthotoxin via the p38-MAPK/HDAC4 pathway

Chondrocyte hypertrophy is a physiological process in endochondral ossification. However, the hypertrophic-like alterations of chondrocytes at the articular surface may result in osteoarthritis (OA). In addition, the generation of fibrocartilage with a decreased biological function in tissue enginee...

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Detalles Bibliográficos
Autores principales: Cao, Zhen, Bai, Yun, Liu, Chuan, Dou, Ce, Li, Jianmei, Xiang, Junyu, Zhao, Chunrong, Xie, Zhao, Xiang, Qiang, Dong, Shiwu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548016/
https://www.ncbi.nlm.nih.gov/pubmed/28677757
http://dx.doi.org/10.3892/mmr.2017.6886