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mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway

Atherosclerosis (AS) is a chronic immuno-inflammatory disease accompanied by dyslipidemia. The authors previously demonstrated that sirtuin 1 (SIRT1) may prevent atherogenesis through influencing the liver X receptor/C-C chemokine receptor type 7/nuclear factor-κB (LXR-CCR7/NF-κB) signaling pathway....

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Detalles Bibliográficos
Autores principales: Zheng, Haixiang, Fu, Yucai, Huang, Yusheng, Zheng, Xinde, Yu, Wei, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548025/
https://www.ncbi.nlm.nih.gov/pubmed/28765952
http://dx.doi.org/10.3892/mmr.2017.7032