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mTOR signaling promotes foam cell formation and inhibits foam cell egress through suppressing the SIRT1 signaling pathway
Atherosclerosis (AS) is a chronic immuno-inflammatory disease accompanied by dyslipidemia. The authors previously demonstrated that sirtuin 1 (SIRT1) may prevent atherogenesis through influencing the liver X receptor/C-C chemokine receptor type 7/nuclear factor-κB (LXR-CCR7/NF-κB) signaling pathway....
Autores principales: | Zheng, Haixiang, Fu, Yucai, Huang, Yusheng, Zheng, Xinde, Yu, Wei, Wang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548025/ https://www.ncbi.nlm.nih.gov/pubmed/28765952 http://dx.doi.org/10.3892/mmr.2017.7032 |
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