Thromboxane A2 receptor antagonist SQ29548 suppresses the LPS-induced release of inflammatory cytokines in BV2 microglia cells via suppressing MAPK and NF-κB signaling pathways

Inflammation in the brain, characterized by the activation of microglia, is hypothesized to participate in the pathogenesis of neuronal disorders. It is proposed that thromboxane A2 receptor (TXA2R) activation is involved in thrombosis/hemostasis and inflammation responses. In the present study, the...

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Detalles Bibliográficos
Autores principales: Yan, Aijuan, Cai, Gaoyu, Xia, Weiliang, Fu, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548048/
https://www.ncbi.nlm.nih.gov/pubmed/28677768
http://dx.doi.org/10.3892/mmr.2017.6884

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548048/
https://www.ncbi.nlm.nih.gov/pubmed/28677768
http://dx.doi.org/10.3892/mmr.2017.6884

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