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Shikonin suppresses proliferation and induces apoptosis in human leukemia NB4 cells through modulation of MAPKs and c-Myc
Acute promyelocytic leukemia (APL) is a special subtype of acute myeloid leukemia that responds to treatment with all-trans retinoic acid and arsenic trioxide. However, severe side effects and drug resistance limit the effectiveness of these treatments. Hence, new drugs for APL are required urgently...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548061/ https://www.ncbi.nlm.nih.gov/pubmed/28713949 http://dx.doi.org/10.3892/mmr.2017.6965 |