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HOXB13 mutations and binding partners in prostate development and cancer: Function, clinical significance, and future directions

The recent and exciting discovery of germline HOXB13 mutations in familial prostate cancer has brought HOX signaling to the forefront of prostate cancer research. An enhanced understanding of HOX signaling, and the co-factors regulating HOX protein specificity and transcriptional regulation, has the...

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Detalles Bibliográficos
Autores principales: Brechka, Hannah, Bhanvadia, Raj R., VanOpstall, Calvin, Vander Griend, Donald J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chongqing Medical University 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548135/
https://www.ncbi.nlm.nih.gov/pubmed/28798948
http://dx.doi.org/10.1016/j.gendis.2017.01.003