Exploiting sequence and stability information for directing nanobody stability engineering

BACKGROUND: Variable domains of camelid heavy-chain antibodies, commonly named nanobodies, have high biotechnological potential. In view of their broad range of applications in research, diagnostics and therapy, engineering their stability is of particular interest. One important aspect is the impro...

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Detalles Bibliográficos
Autores principales: Kunz, Patrick, Flock, Tilman, Soler, Nicolas, Zaiss, Moritz, Vincke, Cécile, Sterckx, Yann, Kastelic, Damjana, Muyldermans, Serge, Hoheisel, Jörg D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548252/
https://www.ncbi.nlm.nih.gov/pubmed/28642127
http://dx.doi.org/10.1016/j.bbagen.2017.06.014

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548252/
https://www.ncbi.nlm.nih.gov/pubmed/28642127
http://dx.doi.org/10.1016/j.bbagen.2017.06.014

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