Microvesicles shed from fibroblasts act as metalloproteinase carriers in a 3-D collagen matrix

This study shows that fibroblasts migrating into a collagen matrix release numerous microvesicles into the surrounding medium. By spreading in regions of the matrix far distant from cells of origin, microvesicles carry metalloproteinase 9 (MMP-9) to act upon the collagen fibrils. As a result, the co...

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Detalles Bibliográficos
Autores principales: Laghezza Masci, Valentina, Taddei, Anna Rita, Gambellini, Gabriella, Giorgi, Franco, Fausto, Anna Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548308/
https://www.ncbi.nlm.nih.gov/pubmed/28936262
http://dx.doi.org/10.1177/1849454416663660

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548308/
https://www.ncbi.nlm.nih.gov/pubmed/28936262
http://dx.doi.org/10.1177/1849454416663660

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