X-rays and metformin cause increased urinary excretion of cell-free nuclear and mitochondrial DNA in aged rats

Activation of cell death in mammals can be assessed by an increase of an amount of cell-free DNA (cf-DNA) in urine or plasma. We investigated the excretion of cf nuclear DNA (nDNA) and cf mitochondrial DNA (mtDNA) in the urine of rats 3 and 24 months in age after X-irradiation and metformin administ...

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Detalles Bibliográficos
Autores principales: Gaziev, Azhub, Abdullaev, Serazhutdin, Minkabirova, Gulchachak, Kamenskikh, Kristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548319/
https://www.ncbi.nlm.nih.gov/pubmed/28936265
http://dx.doi.org/10.1177/1849454416670782

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548319/
https://www.ncbi.nlm.nih.gov/pubmed/28936265
http://dx.doi.org/10.1177/1849454416670782

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