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Activation and expression of μ-calpain in dorsal root contributes to RTX-induced mechanical allodynia

BACKGROUND: Calpain is a calcium-dependent cysteine protease, and inhibition of calpain by pre-treatment with MDL28170 attenuated the rat mechanical allodynia in a variety of pain models. Postherpetic neuralgia (Shingles) is a neuropathic pain conditioned with the presence of profound mechanical all...

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Detalles Bibliográficos
Autores principales: Yuan, Xiao-Cui, Wu, Cai-Hua, Gao, Fang, Li, Hong-Ping, Xiang, Hong-Chun, Zhu, He, Pan, Xiao-Li, Lin, Li-Xue, Liu, Yan-Shen, Yu, Wei, Tian, Bo, Meng, Xian-Fang, Li, Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548329/
https://www.ncbi.nlm.nih.gov/pubmed/28714350
http://dx.doi.org/10.1177/1744806917719169