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Activation and expression of μ-calpain in dorsal root contributes to RTX-induced mechanical allodynia
BACKGROUND: Calpain is a calcium-dependent cysteine protease, and inhibition of calpain by pre-treatment with MDL28170 attenuated the rat mechanical allodynia in a variety of pain models. Postherpetic neuralgia (Shingles) is a neuropathic pain conditioned with the presence of profound mechanical all...
Autores principales: | Yuan, Xiao-Cui, Wu, Cai-Hua, Gao, Fang, Li, Hong-Ping, Xiang, Hong-Chun, Zhu, He, Pan, Xiao-Li, Lin, Li-Xue, Liu, Yan-Shen, Yu, Wei, Tian, Bo, Meng, Xian-Fang, Li, Man |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548329/ https://www.ncbi.nlm.nih.gov/pubmed/28714350 http://dx.doi.org/10.1177/1744806917719169 |
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