A novel region in the Ca(V)2.1 α(1) subunit C-terminus regulates fast synaptic vesicle fusion and vesicle docking at the mammalian presynaptic active zone

In central nervous system (CNS) synapses, action potential-evoked neurotransmitter release is principally mediated by Ca(V)2.1 calcium channels (Ca(V)2.1) and is highly dependent on the physical distance between Ca(V)2.1 and synaptic vesicles (coupling). Although various active zone proteins are pro...

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Detalles Bibliográficos
Autores principales: Lübbert, Matthias, Goral, R Oliver, Satterfield, Rachel, Putzke, Travis, van den Maagdenberg, Arn MJM, Kamasawa, Naomi, Young, Samuel M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548488/
https://www.ncbi.nlm.nih.gov/pubmed/28786379
http://dx.doi.org/10.7554/eLife.28412

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5548488/
https://www.ncbi.nlm.nih.gov/pubmed/28786379
http://dx.doi.org/10.7554/eLife.28412

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